People

Fei Jia

jiafei@him.cas.cn

Biography

Fei Jia earned his B.S. in Chemistry from Jilin University (Changchun) in 2012, followed by a Ph.D. in 2017 from Northeastern University (Boston) under the mentorship of Prof. Ke Zhang. After completing postdoctoral research at the Massachusetts Institute of Technology (Boston) with Prof. Robert J. Macfarlane, Fei established his independent research lab in 2021 at the Hangzhou Institute of Medicine, Chinese Academy of Sciences (Hangzhou).


Research Interests

The Jia Lab specializes in the design and synthesis of novel structured polymers to explore the relationship between materials’ structure and function. Key areas of research include:

         Developing unimolecular polymeric delivery systems for chemical drugs and biologics.

         Creating nanoscale building blocks for functional gels and elastomers.


Selected Publications

Thrasher, C.J.+; Jia, F.+; Yee, D.W.; Kubiak, J.M.; Wang, Y.; Lee, M.S.; Onoda, M.; Hart, A.J.; Macfarlane, R.J., Rationally Designing the Supramolecular Interfaces of Nanoparticle Superlattices with Multivalent Polymers. J. Am. Chem. Soc.2024, 146, 11532–11541.


Jia, F.; Kubiak, J.M.; Onoda, M.; Wang, Y.; Macfarlane, R.J. Design and Synthesis of Quick Setting Non-Swelling Hydrogels via Brush Polymers. Adv. Sci. 2021, 8, 202100968.

 

Jia, F.; Wang, D.; Lu, X.; Tan, X.; Wang, Y.; Lu, H.; Zhang, K., Improving the Enzymatic Stability and the Pharmacokinetics of Oligonucleotides via DNA-Backboned Bottlebrush Polymers. Nano Lett.2018, 18, 11, 7378-7382.


Jia, F.; Lu, X.; Tan, X.; Wang, D.; Cao, X.; Zhang, K. Effect of PEG Architecture on the Hybridization Thermodynamics and Protein Accessibility of PEGylated Oligonucleotides. Angew. Chem.Int. Ed. 2017, 56, 1239-1243.


 

Jia, F.; Lu, X.; Tan, X.; Zhang, K. Facile Synthesis of Nucleic Acid–polymer Amphiphiles and Their Self-Assembly. Chem. Commun.2015, 51, 7843–7846

 

Contacts

E-mail: jiafei@him.cas.cn

Group website:https://www.x-mol.com/groups/feijia

 

Office Room: 1-805

Hangzhou Institute of Medicine

Chinese Academy of Science

150 Fucheng Road, Qiantang District

Hangzhou, Zhejiang Province, China 310000

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