Researchers

Yuan Liu

yuanliu@ucas.ac.cn

Biography

Dr. Yuan Liu graduated with a B.S. degree in Material Chemistry from the Harbin Institute of Technology in 2011. He earned his Ph.D. degree in Chemistry from the University of Florida in 2016. After conducting his postdoc training at NIH and Harvard Medical School, he joined the Hangzhou Institute of Medicine, Chinese Academy of Sciences in May 2021. He has published more than 40 papers in Acc Chem Res, JACS, Matter, ACS Nano et al.

Research Interests

Research interests in Yuan Liu’s lab focus on development of aptamer-based multiplex biomarker discovery and detection, machine learning-based proteome profiling of nanoparticle-protein corona (NPC) for protein biomarker screening and diagnosis, and biological effect of NPC for precise theragnostic, as well as the translational study of nanomedicine and nanotechnology.

Selected Publications

Yuan Liu, Junqing Wang, Qingqing Xiong, Daniel Hornburg, Wei Tao, Omid C Farokhzad.Nano-bio interactions in cancer: from therapeutics delivery to disease detection, Acc. Chem. Res., 2020, 54, 291.

Shuangqin Li, Baichuan Jin, Yintao Ma, Xu Yang, Jinlong Fan, Yueli Xie, Chenlu Xu, Xin Dai, Mengjie Wang, Qiqi Liu, Ting Fu, Yuan Liu, Weihong Tan. Proteome Fishing for CRISPR/Cas12a-Based Orthogonal Multiplex Aptamer Sensing.J. Am. Chem. Soc. 2024, 146, 19874.

Mengjie Wang, Xin Dai, Xu Yang, Baichuan Jin, Yueli Xie, Chenlu Xu, Qiqi Liu, Lichao Wang, Lisha Ying, Weishan Lu, Qixun Chen, Ting Fu, Dan Su, Yuan Liu, Weihong Tan. Serum Protein Fishing for Machine Learning-Boosted Diagnostic Classification of Small Nodules of Lung. ACS Nano, 2024, 18, 4038.

Yuan Liu, Xiaoyuan Chen. Macrophage-targeted gene therapy to improve the atherosclerotic plaque stability. Matter, 2020, 3, 621.

Yuan Liu, Yu Yang, Yujia Sun, Jibin Song, Nicholas G. Rudawski, Xiaoyuan Chen, Weihong Tan Ostwald Ripening-Mediated Grafting of Metal–Organic Frameworks on a Single Colloidal Nanocrystal to Form Uniform and Controllable MXF. J. Am. Chem. Soc. 2019, 141, 7407.

Yuan Liu, Daniel L Purich, Cuichen Wu, Yuan Wu, Tao Chen, Cheng Cui, Liqin Zhang, Sena Cansiz, Weijia Hou, Yanyue Wang, Shengyuan Yang, Weihong Tan. Ionic Functionalization of Hydrophobic Colloidal Nanoparticles to Form Ionic Nanoparticles with Enzymelike Properties. J. Am. Chem. Soc. 2015, 137, 14952.

Yuan Liu, Tao Chen, Cuichen Wu, Liping Qiu, Rong Hu, Juan Li, Sena Cansiz, Liqin Zhang, Cheng Cui, Guizhi Zhu, Mingxu You, Tao Zhang, Weihong Tan. Facile Surface Functionalization of Hydrophobic Magnetic Nanoparticles. J. Am. Chem. Soc. 2014, 136, 12552.

 

Contacts

E-mail: yuanliu@ucas.ac.cn

 

Office Room: 4-203

Hangzhou Institute of Medicine

Chinese Academy of Sciences

150 Dongfang Road, Qiantang District

Hangzhou, Zhejiang Province, China 310000


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